Scientists have tested CBD’s efficacy as an analgesic—and with promising results. Here’s what we know so far about how we can use CBD oil for pain relief. ADVERTISEMENT. San Antonio Current news staff was not involved in the creation of this content. Please note, this report is not meant to treat or… CBD, a non-psychoactive component in cannabis, is emerging as a promising pharmaceutical agent to treat pain and other conditions. Unfortunately, few studies in humans have examined its effectiveness, and the cannabis industry’s profit motive is driving a wave of dubious claims about what CBD can do.
How To Use CBD To Help Manage Pain
Dr. Bindiya Gandhi is an integrative medicine physician with expertise in functional and holistic medicine based in Atlanta, Georgia.
Commissions we earn from partner links on this page do not affect our opinions or evaluations. Our editorial content is based on thorough research and guidance from the Forbes Health Advisory Board.
Table of Contents
- CBD for Pain Relief
- CBD for Chronic Pain
- CBD for Arthritis and Joint Pain
- CBD for Neuropathic Pain
Without the intoxicating properties of its cousin delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD) can provide the human body with a handful of health benefits. Cannabinoids like CBD interact with receptors in the endocannabinoid system, which plays a role in signaling bodily functions, from emotional responses to motor control to energy balance  Mouslech Z, Valla V. Endocannabinoid system: An overview of its potential in current medical practice. Neuro Endocrinol Lett. 2009;30(2):153-179. .
Over the last two decades, scientists have tested CBD’s efficacy as an analgesic, or painkiller, specifically—and with promising results. While research is ongoing, here’s what we know so far about how we can use CBD oil for pain relief.
You May Also Be Interested In CBD Cream From Our Featured Partner
Pain Relief Cream
On Medterra’s Website
Joint & Arthritis, Cream
Rapid Recovery Cream
On Medterra’s Website
250mg, 500mg, 750mg
Muscle Support, Recovery Cream
Manuka Honey Healing Cream
On Medterra’s Website
Rapid Recovery Roll On
On Medterra’s Website
250mg, 500mg, 1000mg
Muscle Support, Roll-on
(Note: Product details and price are accurate as of publication and are subject to change.)
CBD for Pain Relief
For now, no CBD-based medications are approved as painkillers in the U.S. Epidiolex, which is used for rare forms of epilepsy, is the only CBD treatment approved by the Food and Drug Administration (FDA).
Meanwhile, several countries have approved CBD to treat certain conditions. For instance, the U.K. approved it for multiple sclerosis, and Canada approved it for cancer pain. Ongoing research suggests CBD oil for pain can aid medical conditions, including arthritis and fibromyalgia, at varying doses. Some pain may not be treatable by CBD alone, but it can help when paired with THC or Western medication applications.
Interestingly, 60% of U.S. adults who use CBD products do so for its potential pain-relieving effects, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.
What’s more, 60% of U.S. adults have tried CBD and believe it has medicinal benefits.
CBD for Chronic Pain
Chronic pain is defined as any pain lasting longer than several months. Studies have found CBD, often alongside THC, to be an effective pain reliever for various chronic conditions.
In clinical trials, Sativex, a spray with equal parts CBD and THC, proved significantly successful as an analgesic for cancer-related pain  Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. . The spray, also used for multiple sclerosis-related pain, is approved in Canada to treat cancer pain and is currently undergoing trials for approval and use in the U.S.
A 2019 study found Sativex to be an “effective and well-tolerated add-on treatment” for patients with severe chronic pain stemming from various ailments. The study identified three types of pain: nociceptive (affecting body tissue), neuropathic (affecting nerves) and mixed pain. Sativex helped treat all three kinds but proved especially effective against neuropathic pain.
An earlier study also found CBD to be effective in chronic pain relief for conditions like multiple sclerosis and spinal cord injury, although across a much smaller sample size  Wade DT, Robson P, House H, Makela P, Aram J. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Clin Rehabil. 2003;17(1):21-29. .
CBD for Arthritis and Joint Pain
Arthritis is a broad term that encompasses hundreds of joint-related conditions and pains. Common symptoms include swelling, pain and stiffness in the joints and may progress over time.
Already a proven analgesic for other conditions, CBD shows promise as an anti-inflammatory substance in both animal and preclinical trials, which bodes well for arthritis treatment  Nichols JM, Kaplan BLF. Immune Responses Regulated by Cannabidiol. Cannabis Cannabinoid Res. 2020;5(1):12-31.  Mlost J, Bryk M, Starowicz K. Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action. Int J Mol Sci. 2020;21(22):8870.  Kosgodage US, Mould R, Henley AB, et al. Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Front Pharmacol. 2018;9:889.  Lowin T, Tingting R, Zurmahr J, Classen T, Schneider M, Pongratz G. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death Dis. 2020;11(8):714. . However, clinical research dedicated to CBD administration for arthritis is less robust and ongoing.
The first controlled trial conducted in 2006 focused on patients with rheumatoid arthritis, an autoimmune disease that causes inflammation in the joints and other affected areas  Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford). 2006;45(1):50-52. . Researchers found that, compared to a placebo, Sativex significantly improved participants’ pain during movement, pain at rest and quality of sleep. Any adverse reactions to the treatment were mild or moderate, and there were no complications with withdrawal.
In 2018 researchers tested the efficacy of topical CBD gel on participants with osteoarthritis-related knee pain over the course of 12 weeks  Hunter D, Oldfield G, Tich N, Messenheimer J, Sebree T. Synthetic transdermal cannabidiol for the treatment of knee pain due to osteoarthritis. Osteoarthritis and Cartilage. 2018;26:S26. . Participants used either 250 milligrams or 500 milligrams, split into two applications, daily. Overall, participants’ weekly pain levels didn’t improve much with CBD compared to placebo. However, when researchers evaluated the average weekly worst pain scores and Western Ontario and McMaster Universities Arthritis Index (WOMAC) physical function scores, participants who applied 250 milligrams of CBD daily experienced significant improvement over placebo participants.
Meanwhile, a small 2019 trial suggests a mix of CBD and THC may prove beneficial for people with fibromyalgia, a type of arthritis that results in whole-body pain and fatigue  van de Donk T, Niesters M, Kowal MA, Olofsen E, Dahan A, van Velzen M. An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain. 2019;160(4):860-869. . The study found that, via a single inhalation, a CBD-THC solution performed better than a placebo and either substance on its own.
CBD for Neuropathic Pain
Various conditions and injuries that damage nerves or the nervous system can result in neuropathic pain. This kind of pain manifests as tingling, numbness, muscle weakness and a sharp, shooting, burning or stabbing pain.
Multiple sclerosis (MS) is a common cause of neuropathic pain. The disease wears down myelin, a mixture of proteins and phospholipids that coats nerve cells. Sativex is already approved as an MS treatment around the world due to its success in clinical trials. As a spray, Sativex is absorbed in the mouth. Studies support a median dose of eight sprays a day for patients with MS, which provides about 20 milligrams of CBD and 21.6 milligrams of THC  Sativex Oromucosal Spray – Summary of Product Characteristics (SmPC). Datapharm. Accessed 7/9/2021. . However, doses vary between patients, and each person needs to find their optimal dose.
A 2020 study also tested topically administered CBD oil as a treatment for patients with peripheral neuropathy, or damage to the peripheral nervous system, which sends information throughout your body from the central nervous system  Xu DH, Cullen BD, Tang M, Fang Y. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Curr Pharm Biotechnol. 2020;21(5):390-402. . When compared to placebo, the topical CBD significantly reduced patients’ intense pain and sharp pain, as well as cold and itchy sensations.
You May Also Be Interested In CBD Cream Products From Our Featured Partner
How to Manage Pain with CBD Gummies
ADVERTISEMENT. San Antonio Current news staff was not involved in the creation of this content. Please note, this report is not meant to treat or diagnose any illness. It is written for informational purposes only. If you have any health concern at all, please see a licensed healthcare professional.
More and more people around the world are purchasing hemp products due to their promising benefits. As a result, more people are trying out CBD gummies and other products with CBD.
People try to chew CBD gummies for pain. The usual pain meds might have side effects, but CBD oils may get rid of pain much safer. Why not choose CBD gummies for a tasty CBD dose?!
CBD products might help with other problems such as acne and anxiety. Unlike the others, CBD gummies may be fun and healthy. For the best quality, check the best CBD gummies for pain.
What Is Full-spectrum CBD?
Products like CBD gummies contain CBD oils, and it determines their quality and high-potency.
These are a mixture of cannabidiol (CBD), compounds, and select essential oils. Also considered as a cannabinoid, the former comes from industrial hemp extract and cannabis plants.
The best CBD gummies and similar products contain the best CBD oils made of top-quality cannabidiol enhanced and the best essential oils and blends. These include lavender oil and coconut oil, which may enhance the benefits of CBD.
What’s more, they are typically classified as full-spectrum CBD since they contain nearly all materials from cannabis.
Not to be confused with broad spectrum or CBD isolate, full spectrum formulations contain trace amounts of THC and other plant substances that produce an entourage effect. This is the interaction between these ingredients that make the best CBD gummies superior.
What Are The Potential Benefits Of CBD?
As we’ve mentioned, CBD gummies may soothe chronic pain and provide other health benefits.
Aside from CBD gummies for pain, similar goodies may alleviate stress after a long day. Experts found that cannabidiol may induce feelings of relaxation that might destress exhausted people.
Even better, these soothing sensations may help with symptoms of anxiety and depression. It could also ease you into better sleep, helping further with stress and improving mental health.
What Are CBD Gummies?
If you’ve browsed common CBD products online, you might find them unique. In response, you may have wished there was a CBD option that is similar to regular snacks.
Thankfully, CBD gummies are like classic gummy bears, but they contain a set amount of CBD in every chew. Similarly, they come in different flavors, and they have varying CBD concentrations.
These are the perfect choice for a delectable way to take CBD. You’ll find a wide variety of flavors to choose from. You could even find options that fit specific diets!
Of course, your experience will depend on the product’s quality. That’s why you should only chew on the best CBD gummies for pain and other needs.
How To Use CBD Gummies?
There are several reasons for snacking on CBD gummy treats. For example, you could chew CBD gummies for pain, anxiety, and depression.
You could munch on a few while you’re taking a break for a bit of CBD goodness. What’s more, you could take CBD gummies for pain and other conditions. What more could you want with CBD benefits in every bite?
No matter the purpose, you should follow the product’s instructions. The right dose of CBD gummies will keep you safe from unintended side effects. If you feel any unusual symptoms afterward, refrain from taking the product. Please seek medical advice before taking any CBD product.
Your physician can assist you in taking CBD safely by recommending your dose.
CBD Gummies Anxiety & Depression
Besides taking CBD gummies for pain, these cannabidiol bites may also help with mental health.
It may induce soothing sensations for alleviating anxiety and stress. Participants of a study from 2019 exhibited reduced anxiety after taking CBD.
What’s more, the feelings of relaxation from CBD might even help people sleep better. Then, improved sleep may improve mental health further.
Effects will depend on CBD oil quality, though, so you should use the best CBD gummies.
Best CBD Gummies for Pain
With the abundance of CBD choices nowadays, it can be difficult to find truly top-quality CBD gummies for pain. How do you find the best CBD gummies for pain?
First, they should be made with hemp grown in the United States. This ensures every chew contains quality and safety.
Second, it should be lab-tested by third-party lab testing. This verifies the ingredients, that are free of artificial sweeteners, inside the CBD gummies through unbiased scientific results.
Third, the best CBD for pain is created using all-natural and organic ingredients, ensuring a quality product. You won’t find any artificial additives in each piece.
Where do you find the best CBD edibles for pain management? Well, Blosum’s CBD products have top-notch quality and safe CBD gummies for all your needs!
Best Vegan Gummies
Blosum provides Vegan CBD gummies that meet every standard for top-tier quality and supplement.
CBD Gummies Vegan Full-Spectrum
Price: Starting at $74.99
Strength: 10 mg or 25 mg
Flavor: Mixed Fruit (Watermelon, Orange, and Strawberry)
BlosumCBD’s Vegan Full-spectrum Gummies have it all! These all-natural ingredient treats are not only delicious but beneficial for a better quality of life. Each of these full-spectrum gummies contains 0.3% THC, meaning you can get the full effects of benefits like the “entourage effect” from the high potency of the product. Blosum’s Vegan Full-Spectrum Gummies are:
- Grown in the U.S.
- Third-party Lab tested
- Vegan & Gluten-free
- 100% USDA Organic
CBD Gummies Vegan Broad-Spectrum
Strength: 25 mg
- Grown in the U.S.
- Third-party Lab tested
- Vegan & Gluten-free
- 100% USDA Organic
Inferior CBD gummies have a thin veneer of cannabidiol that eventually deteriorates, resulting in inconsistent and weak effects.
On the other hand, cannabidiol is infused in every bite of Blosum’s CBD gummies. Each CBD treat provides a consistent dose of 15 or 25 mg of CBD.
You could try Blosum’s Full-Spectrum CBD Gummies for the taste of watermelon, strawberry, and orange in each bite. They provide maximum CBD effects while keeping vegan-friendly.
Alternatively, Blosum’s Broad-Spectrum CBD Gummies contain 25 mg of CBD, sweet strawberry flavor, and no THC.
- Rich in full-Spectrum phytocannabinoids
- Contains 0.3% THC following FDA standards
- US-made and contains all-natural and vegan ingredients with no GMOs
Experts have researched cannabidiol’s effect on chronic pain and found promising results.
CBD interacts with the body’s endocannabinoid system (ECS), which regulates vital functions such as pain perception and mood. Once cannabidiol binds to its receptors, a person may experience pain relief or help with inflammation.
Most CBD products may soothe muscle aches since they all contain cannabidiol. For example, CBD oil tinctures quickly take effect because it’s applied under the tongue. However, they often dissipate after a short time.
If you want pain relief that doubles as a snack, then you may want to grab CBD gummies for pain. First-timers would likely munch on this chewy treat over the other CBD alternatives. After all, it’s basically like candy with some CBD!
As with any medicine, CBD poses a slight risk for negative effects.
Fortunately, legitimate CBD retailers always follow the Food And Drug Administration’s guidelines. These laws ensure that CBD gummies for pain are generally safe for consumption.
People are likely to experience side effects due to improper CBD dosage and underlying health conditions.
That’s why you must consult a health professional before taking CBD. Also, follow your doctor’s recommendations and the product’s instruction label.
How Long Does It Take To Work?
CBD gummies for pain and other conditions usually take effect after 2 hours.
Your body has to digest ingested CBD before you could experience any effects. Digestion usually takes 2 hours, depending on several factors.
For example, it might work quicker if you take CBD on an empty stomach. Also, it depends on the type and quality of your CBD product.
The best CBD gummies comply with FDA guidelines to ensure customer safety and satisfaction.
You may choose between two ways on how to take CBD gummies.
You could take 25 mg of CBD every day, then add 25mg more every 4 weeks until you’ve achieved the intended effects.
If symptoms worsen, deduct 25mg from the daily dose. Though, you should seek a health professional if CBD oil seems to exacerbate your medical condition.
In contrast, you could start with 25mg then adjust the dosage depending on your symptom relief.
Are CBD Gummies Legal?
The 2018 Farm Bill has allowed hemp-derived CBD products like cannabidiol gummies for public consumption.
Moreover, it mandates that their tetrahydrocannabinol (THC) content must stay at 0.3% or less. It’s the psychoactive component of cannabis, but this limit prevents mind-altering effects in CBD products.
As we’ve discussed, it causes an entourage effect that might enhance cannabidiol gummies’ pain. Most of the best CBD gummies use this chemical reaction to provide the utmost benefits.
What’s more, they comply with FDA quality and safety standards. They adhere to the strict THC limit and consist of all-natural and organic ingredients.
However, each state has different CBD regulations, so please check your local CBD laws and comply accordingly.
Do CBD Gummies Get You High?
You’re unlikely to experience psychoactive effects from doses of cannabidiol gummies.
While there are THC-free variants, you could purchase, full-spectrum CBD gummies generally don’t cause mind-altering effects.
The best gummies with CBD strictly comply with FDA guidelines to prevent adverse effects.
Always buy top-quality CBD gummies for pain and other needs.
What are the Pros and Cons of Using CBD Gummies?
All products pose some risk, but they’re unlikely in cannabidiol gummies.
Side effects may include reduced appetite and drowsiness, but they often result from improper use. You could choose products made with pure CBD isolates, but other substances won’t improve its cannabidiol.
If you use the best CBD gummies for pain, you avoid these potential side effects. They comply with strict FDA regulations to keep their customers safe and satisfied.
What’s more, CBD gummies allow for a delectable CBD experience! Even better, BlosumCBD products provide excellent customer service!
These statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease. Always check with your physician before starting a new botanical extract, medicinal herb, or dietary supplement program. Hemp-derived CBD products (with less than 0.3 percent THC) are legal on the federal level but are still illegal under some state laws. Check your state’s laws and those of anywhere you travel. Keep in mind that nonprescription CBD products are not FDA-approved.
The statements made in this sponsored post are those of the paid sponsor and not those of San Antonio Current, and are not intended as medical advice. Consult your doctor before undertaking any changes to your physical, mental or dietary health.
Join the San Antonio Current Press Club
Local journalism is information. Information is power. And we believe everyone deserves access to accurate independent coverage of their community and state.
Help us keep this coverage going with a one-time donation or an ongoing membership pledge.
Evangelical church no longer plans to operate from public school in Mahncke Park, officials say
By Sanford Nowlin
San Antonio’s CommonWealth Coffeehouse taking over former Rosella location on Jones Avenue
CBD for chronic pain: The science doesn’t match the marketing
If you ask health care providers about the most challenging condition to treat, chronic pain is mentioned frequently. By its nature, chronic pain is a complex and multidimensional experience. Pain perception is affected by our unique biology, our mood, our social environment, and past experiences. If you or a loved one is suffering from chronic pain, you already know the heavy burden.
People are looking for novel, nonaddictive ways to treat pain
Given the ongoing challenges of chronic pain management coupled with the consequences of the opioid epidemic, pain management practitioners and their patients are searching for effective and safer alternatives to opioids to alleviate pain. With the legalization of marijuana in many states and resulting cultural acceptance of this drug for recreational and medical use, there has been an increased interest in using cannabis for a myriad of medical problems, including pain.
Cannabis (most commonly obtained from the Cannabis indica and Cannabis sativa plants) has three major components: cannabinoids, terpenoids, and flavonoids. While there are over a hundred different cannabinoids, the two major components are tetrahydrocannabional (THC) and cannabidiol (CBD). Historically more attention has been paid to the psychoactive (euphoric “getting high”) component of the cannabis plant, THC; there have been fewer scientific studies on the medical use of CBD, a non-psychoactive component of the plant.
What’s the thinking behind using cannabis for chronic pain?
CBD is emerging as a promising pharmaceutical agent to treat pain, inflammation, seizures, and anxiety without the psychoactive effects of THC. Our understanding of the role of CBD in pain management continues to evolve, and evidence from animal studies has shown that CBD exerts its pain-relieving effects through its various interactions and modulation of the endocannabinoid, inflammatory, and nociceptive (pain sensing) systems. The endocannabinoid system consists of cannabinoid receptors that interact with our own naturally occurring cannabinoids. This system is involved in regulating many functions in the body, including metabolism and appetite, mood and anxiety, and pain perception.
What’s the research that CBD works in humans?
Given its promising results in animal models, along with its relative safety, non-psychoactive properties, and low potential for abuse, CBD is an attractive candidate to relieve pain. Unfortunately, there is a lack of human studies about the effectiveness of CBD. However, there is an abundance of commercial advertisements about the magical effects of CBD, and it is frequently presented as a cure-it-all potion that will treat everything including diabetes, depression, cancer, chronic pain, and even your dog’s anxiety!
So far, pharmaceutical CBD is only approved by the FDA as adjunct therapy for the treatment of a special and rare form of epilepsy. Currently, CBD alone is not approved for treatment of pain in the United States. But a combination medication (that contains both THC and CBD in a 1:1 ratio) was approved by Health Canada for prescription for certain types of pain, specifically central neuropathic pain in multiple sclerosis, and the treatment of cancer pain unresponsive to optimized opioid therapy. There is currently no high-quality research study that supports the use of CBD alone for the treatment of pain.
Why is CBD presented to the public this way, when it is not without risks?
Given the rapid change in the legality of cannabis coupled with the increased appetite for something new, and driven by unprecedented profit margins, the advertising for cannabinoids in general and CBD in particular has gone wild. The FDA is very clear that it is illegal to market CBD by adding it to a food or labeling it as a dietary supplement. And it warns the public about its potential side effects, as it’s often advertised in a way that may lead people to mistakenly believe using CBD “can’t hurt.” CBD can cause liver injury, and can affect the male reproductive system (as demonstrated in laboratory animal studies).
Most importantly, CBD can interact with other important medications like blood thinners, heart medications, and immunosuppressants (medications given after organ transplantation), potentially changing the levels of these important medications in the blood and leading to catastrophic results, including death. Also, more information needs to be gathered about its safety in special populations such as the elderly, children, those who are immunocompromised, and pregnant and breastfeeding women.
Many of the CBD products on the market are unregulated
In fact, the FDA has issued several warning letters to companies and individuals that market unapproved new drugs that allegedly contain CBD. The FDA has tested the chemical content of cannabinoid compounds in some of the products, and many were found to not contain the levels of CBD the manufacturers had claimed they contain.
Beware of powerful testimonials
Finally, there is anecdotal wisdom, when experiences by patients and health professionals have positive results. While the experience or medication could be beneficial, that doesn’t mean it is going to work for everyone. That’s because each and every person is unique, and what works perfectly for one patient could have no effect on another patient. This is especially true for pain, where many other factors (our mood and stress level, our environment and other medical conditions, and our previous experiences) can affect the perception of pain. Please be careful, and keep in mind that some of these incredible-sounding testimonials are merely marketing materials meant to lure consumers to buy more products, as the CBD market is expected to hit $20 billion by 2024.
The bottom line: Don’t make CBD your first or only choice for pain relief
If you or someone close to you is considering trying CBD, I would recommend Dr. Robert Shmerling’s advice about the dos and don’ts in choosing an appropriate product. Until there is high-quality scientific evidence in humans, it is difficult to make a recommendation for the regular use of CBD in chronic pain management.
About the Author
Shafik Boyaji, MD , Contributor
Dr. Boyaji earned his medical degree from University of Aleppo, Syria. He completed an Internal Medicine residency at Michigan State University and an Anesthesiology residency at the Brigham and Women’s Hospital. Currently he is in fellowship … See Full Bio
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
Ive been in persistent ache for 10 years. I’ve been the usage of Kratom and marijuana to deal with the ache. I would not be alive these days with out the kratom. I became the usage of hydrocodone which became a terrible enjoy mentally and physically. Recently my canine evolved a hip trouble wherein she should not walk. The groomer started out making use of cbd oil and in quick time she became lots higher It’s an absolute miracle. Marijuana is a plant now no longer a drug and additionally hemp has come to be a superfood. Marijuana became maximum possibly made unlawful to guard the earnings of pharma.