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good shit man

Good shit man

Raymond has still not had a recurrence of his C. diff.

The impact of Ray’s FMT on his future leukaemia treatment is not known. Nor is its impact on his ability to safely metabolise his long list of medicines. FMT was the choice between life and death, so survival made these risks worth taking for him. But for patients engaging in trials for more chronic health conditions, where the benefit of FMT is less clear, this risk-benefit equation remains harder to quantify.
So how would you feel if that sandwich was rebranded as a faecal microbiota transplant (FMT) , made up of a newly discovered organ called the “gut microbiome ”?

The logistics of preparing an FMT should not be underestimated. Faecal donors have to be found and this is harder than you might think. Most of us are squeamish about pooing in pots and we struggle to do it on demand. Some studies use friends and families, some use members of staff, volunteers or “pooled” samples taken from lots of donors mixed together. The complexity and demand for faecal transplants has spawned an entire industry, and FMT can now be purchased frozen from biobanks and in capsules (or to be more precise “crapsules”). But, just as with any organ donation, donors have to be carefully screened to make sure that they do not harbour diseases or parasites that could be transferred to the patient. Potential stool donors therefore undergo a rigorous screening questionnaire, medical interview and examination, followed by blood and stool testing.
He finds the gut dealing with climate change. Industrialised modern life is scorching our inner worlds much as it is the planet.
Three days after he had returned home, Ray’s son called an ambulance. Ray was readmitted to St Mary’s critically unwell and was soon diagnosed with Clostridioides difficile infection (also known as C. diff or CDI). This disease is a “hospital acquired infection”, a complication of twentieth-century medicine and an unintended consequence of Fleming’s discovery. It is a global problem that afflicts 500,000 people in the United States each year and kills 29,000 of them. It typically afflicts the elderly or those with multiple medical problems and a vulnerable immune system. Ray was a sitting duck.
M odern medicine has gone to shit. Yes, hospital waiting times are too long, healthcare is too expensive and there are not enough nurses. But medical science has turned to waste in a more literal sense. Because actual human waste may hold the key to the world’s most pressing health challenges.
Nonetheless, FMT is now being investigated with varying success in 268 trials listed on clinicaltrials.gov. These include such varied conditions as inflammatory bowel disease , irritable bowel syndrome, obesity, acute malnutrition, diabetes, arthritis, hepatic encephalopathy , liver transplant, melanoma , Sjögren’s syndrome , Alzheimer’s, autism, bipolar disorder, alopecia, amyotrophic lateral sclerosis , and recurrent urinary tract infections.

I know, I know. There’s so much hype in health journalism. But the study of the gut microbiome – the universe of bacteria living in our intestine – really is opening up a new age in our understanding of the human body that promises to unlock revolutions in drugs and healthcare, food and nutrition, wellbeing and even happiness.

Good shit The new frontier of medical science is closer than you think – much closer. It lies within us, in the bacteria and viruses of the gut, and in the mysterious efficacy of faecal

Good shit man

I was introduced to Crocs at the age of 19 by my friend Beth. I was visiting her in Chicago and she was wearing a kelly green pair around the city. Her explanation: “Flip-flops are disgusting, especially in a city, but Crocs are great.” This is actually 100% true and correct, but it didn’t take long for me to fall out of love with the hot pink pair I bought. After that, I didn’t really think much about Crocs again.

Image: Kiyana Salkeld / Just Good Shit
In other family clog news, my girlfriend bought a pair of white Dansko clogs a couple of months ago that look great on her. Danskos are a whole other ugly cool shoe story, but I like my gfs so much (way more than I expected to). I might get a pair eventually, but I do think Danskos make more sense as real world shoes vs. house shoes.

By the way, when I told my mom I was writing this blog post, she told me I had to interview her for it. This is fair; my mother is basically a sneakerhead…but for Crocs. She was into Crocs before Post Malone or Madewell were. She has 20 pairs and counting (!!), and and her collection includes some limited editions.
How This Matching Sweatsuit Became The Unofficial Uniform Of Quarantine, Refinery29.
I have heard bad things about how Entireworld sweatsuits look IRL, but I am very here for a monochromatic sweatsuit.
If you want a lower-lift/less frequent option, you could email yourself or add to a Google Doc once a week.
Have a good Sunday night! 🌙
Also, VICE Life launched How to Stay In, to make it a little easier to find all of the coronavirus-related service journalism that teams across editorial have been putting out for the past month.

(If you’re a bookseller, librarian, or reviewer, you can request an e-galley on NetGalley. And if you have other questions about getting an advance or want to set up an interview, you can email Jennifer Hergenroeder.)

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