The surge then triggered more frequent feeding in the rats when compared to a control group. They also tested rats that were given an anti-ghrelin drug, which prevented this surge after cannabis exposure. These rats ate normally, showing the researchers the essential role THC plays in promoting hunger through a hormone surge .
As you may already know, cannabis contains hundreds of compounds, many of which have medicinal benefits. All cannabinoids interact with our endocannabinoid system, which, among other functions, controls appetite. Of particular importance for appetite stimulation is tetrahydrocannabinol (THC). It has a lengthy history of study for this very purpose.
A meal packed full of cannabinoids does have a slightly different effect than a non-infused version. Let’s take a mini biology lesson on digestion and cannabis.
Food is absorbed in the small intestine, never in the stomach. The stomach completes most of the digestion that started in the mouth, with the exception of fats. These are finished off in the small intestine.
The Prince of Pot has extrapolated information from a Sativex study with the intent to explore the effects of cannabis on an empty stomach versus on a full one. Sativex is a pharmaceutical cannabis preparation in an oral spray format. While some spray absorbs in the mouth, much of it is swallowed. As such, the results from this study translate well for edibles.
Thankfully, THC for appetite stimulation is a well-studied topic . In trial after trial, cannabis boosts appetite, especially in cases of chronic disease-stimulated anorexia . Over the years, researchers have performed many studies on animals, exploring the connection between THC and the munchies.
The Sativex study showed that when we consume cannabis on an empty stomach, peak THC levels hit the bloodstream much faster than when on a full stomach. We may absorb more THC if we eat beforehand, but the onset of effects is much slower. Eating creates a time-release effect for longer lasting and better medicinal benefit.
This isn’t news to anyone already using edibles, but a confusing surprise for anyone unfamiliar with the format. How can eating something make you hungrier?
What this shows us is that when we eat a meal, it helps our digestive tract properly regulate the release of medicine. On an empty stomach, the cannabis floods into the lower intestine and overwhelms the system. These may be unpleasant for you.
Edibles: Don’t Eat On An Empty Stomach Share this: It might seem odd to be advised to eat before consuming edibles, but this is true of many medicines. You may already know this,
Instead, approach edibles or any consumption method the same whether fully fed or starving: start low and go slow. Pacing out doses is always wise, even if the products come from reputable brands. That said, fight the urge to gorge on edibles if you do go in with an empty stomach. Have a non-THC snack in hand. Bonus points if you have CBD on hand nearby. If the adverse effects of an empty stomach high kick in, a CBD product may help offset the negative effects. Either way, consume safely, friends.
Do you think consuming cannabis on an empty stomach increases effects? Why or why not? Share your experiences below!
In one case, The Prof of Pot pointed towards studies such as the 1999 study which found THC to delay digestion by almost 50 percent. Additionally, they highlighted a 2012 study which found that THC and CBD were absorbed quicker on empty stomachs compared to those who were well fed. That said, the Prof elaborated that total absorption of cannabinoids was higher in those that ate prior to consuming. They elaborated, “Although food did delay the time to peak concentrations, the actual levels were otherwise very similar.”
D o you feel stronger cannabis effects on an empty stomach? This is likely a question most have asked about countless foods, drinks and much more we consume in our lives. Often, we tend to wonder how different experiences would be when we don’t eat before consuming. Why that is the case is far from certain. Regardless, it is a topic long discussed. More often than not, these debates lack any conclusion and leave many to go off of their own experiences and anecdotal findings. PotGuide readers have asked us to address this situation and try to unearth a definitive answer on whether or not you get higher on an empty stomach. For those seeking such an outcome, there still isn’t a whole lot of concrete information. Nevertheless, we tried our best to provide some sort of answer.
In this writer’s case, situations vary. Empty stomachs and the rest of the day’s factors certainly play into how your high will turn out. While an edible seems to be the method of consumption most likely to impact you on an empty stomach, conflicting data and personal reports leave us with no clear answers.
The effects of an empty stomach are often brought up when discussing a person’s vice of choices. Alcohol consumption and hunger have long been discussed. That includes a 1993 study of nine participants, six men and three women. Researchers tested subjects’ drinking during a full stomach and after a few hours of going hungry, with the tests separated by one week. Unsurprisingly, the data found that the effects of alcohol took longer to react on subjects who had recently eaten, while the overall level of consumption remained the same throughout all scenarios – much like cannabis.
Even sex has come into question. The common perception seems to be that unlike most other things, you should engage in the act of coitus on an empty stomach. With the amount of energy it takes the body to digest a meal, a person’s stamina may be diverted from what it takes to meet the demands of their partner(s). Plus, a full stomach potentially leaves a person feeling bloated, tired and not looking how they may want to when it’s time to get to business.
Cannabis research lags pretty much across the board at this point. Significant points of concern surrounding patient care, mental health and scores of other pressing concerns lack the needed research due to the current prohibition in countries such as the United States. So, it should come with little surprise that research into the efficacy of consuming cannabis on an empty stomach remains minimal at this time. That said, the importance of the issue impacts several consumption experiences from the desired effect a patient needs to get through the day to how stoned someone wants to be out in the world.
For coffee and tea lovers, an empty stomach’s effect on caffeine absorption can leave some feeling sick to their stomachs, with achey heads or jittery limbs. In some cases, physicians have gone so far as to suggest drinking coffee in the mid-morning or early afternoon rather than straight out the gate in the morning. Dr. Adam Simon told Express in 2017 that consuming caffeine on an empty stomach can lead to damaged stomachs and mood changes as well. This may one day prove true that those people that say you shouldn’t talk to them until they’ve had their coffee are actually accurate.
Many people have asked us, do you get higher on an empty stomach? We set out to find the answers to this sometimes ambiguous question. Keep reading to learn whether or not consuming cannabis on an empty stomach has any impact on overall effects.