A single dose of cannabidiol can decrease anxiety and tremors in Parkinson’s patients during situations known to induce anxiety, a study found. Looking for the best CBD oil for tremors? Look no further. This handy ranking provides pictures, videos, and reviews of the top hemp-based CBD oils.
Cannabidiol Found to Reduce Anxiety-induced Tremors in Parkinson’s Patients, Study Shows
A single dose of cannabidiol (CBD) can decrease anxiety and tremor strength in people with Parkinson’s disease during situations known to induce anxiety, such as a public speaking exercise, a study found.
Cannabidiol — and the different molecules found in the Cannabis sativa plant — has attracted much attention since its widespread legalization. One of the main components of the plant, CBD does not have psychoactive properties, unlike tetrahydrocannabinol (THC), the main hallucinogenic component of cannabis.
It does have anxiolytic, or anxiety-reducing properties.
Given that, and due to its anti-inflammatory and neuroprotective properties, CBD has been studied for use in a number of conditions, namely epilepsy — where it is approved to treat certain types of the disorder — inflammatory diseases, cancer, psychiatric disorders, and neurodegenerative diseases.
CBD also has been tested in a number of anxiety studies and has previously been shown to decrease anxiety in healthy volunteers. Now, researchers tested the potential of CBD as an anti-anxiety treatment for people with Parkinson’s.
In addition to motor symptoms, such as tremors and freezing, Parkinson’s also is characterized by several non-motor symptoms, including anxiety. Around 67% of people with the neurodegenerative disease have reported this symptom, with anxiety-inducing situations aggravating their Parkinson’s tremors.
The anxiety treatments currently available, such as selective serotonin inhibitors — the most commonly prescribed antidepressant — and benzodiazepines, have side effects which aggravate Parkinson’s symptoms.
The researchers say better options without side effects are needed for treating anxiety, especially in the elderly and in this particular patient population.
So far, cannabidiol has been described as safe, and seems to have very few side effects, making it a good prospective treatment option. However, scientists say more studies are necessary to evaluate CBD, as it is crucial to confirm that the treatment does not interact with other parkinsonian medications.
To learn more, a team of Brazilian researchers conducted a clinical trial in which 24 people with Parkinson’s disease, mean age 64.13 years, took a single, 300 mg dose of CBD or a placebo 90 minutes before being asked to do a public speaking test. This is a common way of inducing anxiety in an experimental setting. The participants had to give a talk on a subject such as “transportation in their city” and were recorded while doing so. They were told that the videos would be analyzed by a psychologist.
The participants all reported the onset of Parkinson’s symptoms after age 50, and had a mean disease duration of 6.5 years. Most individuals were taking levodopa (19 patients) as well as other medications.
All of the patients took part in two experimental sessions within a 15-day interval, during which their blood pressures, heart rates, tremors, and moods were measured at different time points.
The scientists found that the amplitude of tremors was significantly lower in patients who received cannabidiol compared with placebo — and CBD also significantly reduced the anxiety level. There were no differences in any of the other measurements between the CBD and placebo groups.
“These observations suggest that CBD may be an alternative treatment for patients with PD and anxiety,” the researchers said.
CBD’s mechanism of action is not well-understood, since it has many different targets in the brain. Two targets, serotonin 1A receptor (5-HT1A) and cannabinoid receptor type 1 (CB1), have previously been linked to anxiety. As such, the researchers said the interaction of CBD with 5-HT1A and CB1 could in part explain how the compound might be working.
The investigators noted that the study has several limitations. One was its small size — only 24 people participated, 22 of whom were men. In addition, the speaking test was done just 90 minutes after taking CBD. More time might have been needed to see the full effect of the treatment, they noted. The study also lacked active comparators for CBD, such as other anti-anxiety therapies.
Despite these drawbacks, the initial results are promising enough to warrant further investigation into how CBD works in the brains of Parkinson’s patients, the researchers said.
“This is the first study that shows the anxiolytic effects of CBD in patients with PD and its ability in attenuation of the tremor amplitude in anxiogenic situations,” they said.
The investigators suggest future experiments should include more patients and different doses of cannabidiol, for example, having participants take CBD every day instead of in a single dose. Further research is necessary to confirm the calming effects of CBD and what quantity and frequency is optimal for the best results in people with Parkinson’s, they said.
CBD for Tremors
Tremors are muscle movements that involve and back and forth rhythmic swaying. I think you’ll agree with me that those who experience them seem to be uncomfortable. In today’s post, we’ll explore what tremors are and what we know about them.
Best CBD Oils For Tremors
Are tremors really that out of control?
Tremors are involuntary and can impact the legs, hands, arms, head, face, body, and voice. Generally, tremors are caused by neurological dysfunction in the brain affecting how muscles are controlled. Conditions that destroy or degrade the brain like stroke or a brain injury can cause tremors.
Tremors can occur in otherwise healthy people. Those with tremors may experience anxiety or embarrassment because they are visible and can affect one’s motor skills. The rhythmic shaking may be exacerbated by stress or environmental triggers making the motions more extreme and uncoordinated.
Tremors can also occur in reaction to certain prescription drugs or alcohol withdrawal. They can be inherited or appear seemingly randomly. Tremors affect men and women equally and tend to be found in middle age to older people, although anyone can experience them.
Warning : this calculator is for informational purposes only. Talk with your Doctor before taking CBD. Individual results vary, and in fact it is already known that individuals have wildly different results with CBD.
The two types of tremors
Tremors can be classified in two different ways. A resting tremor is when shaking occurs even when a person or muscle is at rest. Parkinson’s patients commonly experience these — their hands will shake even if they are laying down and their hands are resting on their lap. Resting tremors can occur in any area of the body but are most commonly found in the hands and fingers.
Action tremors are a bit more complicated. Action tremors — you guessed it — occur when the individual or affected body part is in motion. There are several subtypes of action tremors. According to the National Institute of Health, there are 5 different action tremor subtypes:
- Postural tremor occurs when a person holds a position against gravity, such as outstretching the arms
- Kinetic tremor is associated with any voluntary movement like opening and closing the eyes
- Intention tremor occurs with purposeful movement towards a target, like reaching to grab something, these can get worse as the person gets closer to the target
- Task-specific tremors occur when performing highly-skilled goal-oriented tasks like writing or speaking
- Isometric tremor occurs during a voluntary muscle contraction that is not accompanied by any movement, like holding a bag
Doctors will evaluate tremors based on neurological and physical examination. Doctors will examine where the tremor occurs in the body when it occurs (acting or resting), and the frequency and amplitude of the tremors. Those with Parkinson’s commonly experience tremors. In a blog post on the Cleveland Clinic’s website, Hubert Fernandez, MD, Director of the Cleveland Clinic’s Center for Neurological Restoration, states, “ Parkinson’s motor problems are quickly recognizable. The tremors — rhythmic movement of lips, chin, hands, and legs; rigidity; stiffness and slowness are hallmark signs. Balance and gait problems are also common. But, Parkinson’s symptoms start long before these problems emerge. As a progressive disease, Parkinson’s destroys the brain’s nerves from the bottom up.” He also states that “only a neurologist can diagnose Parkinson’s” and encourages those who may think they have Parkinson’s to get a neurologist involved earlier.
How are tremors being treated?
There is generally no cure for tremors, but symptoms can be managed given a proper and accurate diagnosis. In some cases, they can be stopped entirely if the underlying cause is removed. For example, those who experience tremors as a side effect of medication or who have a hyperthyroid may see a total change by stopping the medication and balancing the thyroid. For degenerative diseases like Parkinson’s, this is not the case. It’s important to have a thorough testing done to find out the underlying cause.
Here’s what it boils down to:
Tremors can be treated through either medication, surgery, or lifestyle changes. Beta-blocking drugs, anti-seizure medications, tranquilizers, injections, and Parkinson’s disease medications can all treat tremors. In severe cases, surgery may be called for especially for those who don’t respond to drug treatment. Deep brain stimulation (DBS) is the most common form of surgical treatment for tremors and is preferred because it is low risk and effective. DBS sends electrical signals to the thalamus, an area of the brain that coordinates involuntary movements. Another surgical option, a thalamotomy, involves exact removal of a small area of the thalamus.
Patients may also make lifestyle changes in physical, speech, and occupational therapy. Seeing licensed professionals can help people improve their muscle control through training and exercises. In addition, removing stimulants like caffeine or tremor-inducing medications can help as well.
Is there an alternative way?
People are increasingly turning to plant medicine for a low-cost, holistic approach to treating their tremors. Anti-seizure medications and tranquilizers are common prescriptions to treat tremors that can have heavy side effects on the body. Cannabis and CBD are also anti-seizure compounds that can have tranquilizing effects that tend to soothe the body.
In regards to Parkinson’s, Dr. Fernandez states, “it’s important to remember that everyone’s experience with Parkinson’s is different, and treating it is about targeting the symptoms,” he says. “The most important thing is getting a good evaluation by a neurologist or Parkinson’s expert to make sure you’re on the right path.” He emphasizes that treatment is symptom dependent and drugs are prescribed based on how much the tremors interfere with someone’s life.
The cause of Parkinson’s is largely unknown, but doctors do know that dopamine is not produced in high enough quantities in Parkinson’s patients. Dopamine, a neurotransmitter, is naturally produced in the brain and is important in regulating movement in the body. CBD interacts with dopamine receptors and opioid receptors, but more research is needed to thoroughly understand this reaction.
So what’s the most common form of tremors?
Hand Tremors. Hand tremors are the most common form and can make the quality of life really difficult for those who experience them. Writing and motor tasks, like drinking, can be tough and people who live with tremors may experience anxiety and depression, which is also impacted by CBD and cannabinoids.
It’s really important to understand what is causing your tremors and what your treatment options are. Cannabis as medicine is exploding in popularity in places like the United States where it is used to treat seizures, chronic pain, and neurological disorders like Post Traumatic Stress. It’s important to stay proactive about your health and learn as much as possible through trained professionals about your specific conditions.
Click this link to see our CBD reviews
Top Cannabis Product Reviews
Hit The “Sign Up” button below and CannaInsider will send you an occasional e-mail about the most exciting and interesting new products in the cannabis marketplace. We review the most popular CBD oils, vaporizers, cannabis accessories, and more. Get started by hitting the orange sign up button below now!