Can I Mix CBD Oil With Melatonin


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There is a body of research to indicate that CBD oil and melatonin work synergistically to help people get better sleep, and they are considered safe to take together as a sleep aid. Taking CBD oil and melatonin together is largely considered safe, and may be more effective at beating insomnia than taking the supplements on their own

Can You Take CBD with Melatonin?

Both melatonin and CBD are often touted for their ability to help people fall asleep faster and stay asleep longer; with minimal side effects or safety concerns. For optimal effect, you may wonder if it’s safe and effective to combine the two sleep aids. And while it’s usually best to leave the combining of products to professionals like pharmacists and reputable manufacturers, you may find that using pre-existing products that contain both CBD and melatonin can help you enjoy even greater therapeutic benefits—including more restful sleep.

6 Benefits of Taking CBD and Melatonin

  1. Natural
  2. Available Over the Counter
  3. Easier to Fall Asleep
  4. Helps You Stay Asleep
  5. Reduces Anxiety
  6. Corrects Circadian Rhythm

Healthy sleep quality is absolutely essential to our optimal health and well-being, and according to the U.S. Centers for Disease Control and Prevention, roughly one third of Americans get less sleep than the recommended seven-hour minimum. But getting a natural sleep aid with high safety and efficacy may be easier than you think. Both CBD oil and melatonin have long been recognized for their abilities to help people fall asleep, stay asleep longer, and enjoy more restful, restorative sleep. And while for some people it might seem like a no-brainer to use products that combine the two, others may feel a bit of hesitation about combining supplements. But rest assured – as long as you’re using a product from a knowledgeable, reputable manufacturer that contains both CBD oil and melatonin, you should observe increased benefits with no negative side effects from your sleep aid.

As always, when adding a supplement to your health and wellness routine, it’s a good idea to talk with your doctor or pharmacist about potential benefits, side effects, and interactions with any other medications you may already be taking. You want to make sure you’re aware of any potential melatonin or CBD oil drug interactions .

Can You Take CBD with Melatonin?

There is a body of research to indicate that CBD oil and melatonin work synergistically to help people get better sleep, and they are considered safe to take together as a sleep aid. Melatonin is a naturally occurring hormone, produced by the pineal gland, that tells the body it is time to sleep. CBD also shows documented benefits that can translate to better sleep. However, the benefits of using the two active ingredients together seems greater than using either one on its own.

The beauty of the synergy between CBD oil and melatonin is that the strength of each complements the other. But the way the two mix together is important. They need to be used in combination using exact ratios to get the greatest therapeutic effect. You can’t randomly mix together a CBD product and a melatonin product and expect to get good results. The concentration of both, along with the combination of additional cannabinoid compounds in the CBD oil, must be measured and dosed precisely to get the desired result. That’s why it’s best to use a product manufactured with both melatonin and CBD oil.

Melatonin affects the sleep wake cycle via regulation of both the melatonin 1a and melatonin 1b receptors—which are the main melatonin receptors in the human body. And while melatonin plays a vital role in regulating the sleep wake cycle, it will not necessarily put you to sleep effectively. Instead, the hormone’s main job is alerting the brain that it’s time to fall asleep. This is where CBD oil comes in as a sleep aid.

CBD is one of more than 100 powerful cannabinoid compounds naturally found within the cannabis sativa or hemp plant. And while melatonin may signal to your body that it’s time to go to sleep, CBD oil can help your brain activate the right neurotransmitters that help you stay asleep. This makes them a potent combination that helps you fall asleep and stay that way for a night of restful sleep.

Both the MT1 and MT2 melatonin receptors and the CB-1 and CB-2 CBD receptors that influence restful sleep are part of a category called G-protein-coupled receptors. They share a similar structure, process, and mechanism of action—which may explain why CBD oil and melatonin complement each other so well.

You can find CBD oil and melatonin hybrid products in many forms, including oils, tinctures, and gummy or CBD capsule forms. One of the most effective ways of using a sleep aid containing melatonin and CBD is to place a few drops of an oil or tincture under your tongue—this allows the active chemical compounds to bypass the digestive system and almost immediately be absorbed into your bloodstream. Many people who use a CBD/melatonin combo product this way report quickly falling into a light sleep, followed by moving into a deep REM cycle within an hour of using the product.

6 Benefits of Taking CBD and Melatonin

Let’s take a closer look at some of the chief benefits you may experience when using a product that combines CBD oil and melatonin.

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1. Natural

Both CBD and melatonin are naturally occurring, meaning they exist independently in nature and are not formulated in a lab. By using a natural ingredient, like melatonin or CBD, rather than a pharmaceutically engineered sleep aid, you can avoid potential negative side effects, like excessive daytime sleepiness, sleepwalking, and even long-term dependency, which are often associated with prescription medication.

Neither CBD nor melatonin have been shown to have these side effects. And while certainly additional research is needed, all current indications are that CBD oil and melatonin are safe to take together since they interact with the body in different ways.

2. Available Over the Counter

Both CBD oil and a melatonin supplement are easily purchased without a prescription, making them much easier and quicker to access than pharmaceutical sleep medications, which are only available with a doctor’s prescription. Once you’ve spoken with your physician and decided to add a CBD sleep aid to your health and wellness routine, you can easily find one that meets your needs.

3. Easier to Fall Asleep

Since the body naturally produces melatonin, supplementing with additional melatonin often helps with insomnia and other sleep issues. Melatonin levels naturally rise in lower levels of light, which is why it’s common for people to start to feel sleepy when it gets dark at night. However, melatonin production can decrease as we age, making it harder to fall asleep on our own. Melatonin production can also be hampered by environmental factors. In particular, melatonin production can be inhibited by exposure to artificial light, such as those from televisions, computers, tablets, and smartphones. This represents a powerful influence over our melatonin levels given the amount of time our population spends in front of devices. Insufficient melatonin production can result in insomnia or other sleep issues, but supplementing with additional melatonin can help make sure you actually feel sleepy when you go to bed at night.

Note that a melatonin supplement won’t instantly knock you out—it simply prepares your brain and body to rest. Our normal production of melatonin usually begins to rise a couple of hours before it’s time to sleep, and it begins to decrease once we’ve been asleep around six hours, which signals the body that it’s time to move toward wakefulness. Combining melatonin with the natural relaxing power of a CBD product can make it that much easier to fall asleep.

4. Helps You Stay Asleep

Many people have found that taking a melatonin supplement helps reduce the chances that they’ll wake up during the night. Additionally, a study published in the Journal of Psychopharmacology found that small doses of a CBD product increased total sleeping time for rats involved in the study, even during light periods of the day. CBD interacts with serotonin and GABA receptors in the brain, improving mood and decreasing anxiety, which leads to more restful sleep. And there’s early evidence to indicate that using CBD oil and melatonin together may be more effective at helping you stay asleep all night than using either product on its own.

5. Reduces Anxiety

CBD products have been shown to help reduce feelings of anxiety and stress, along with inducing a feeling of calm. Lowered stress levels and an overall sense of calm can aid in helping people relax, fall asleep faster and get more restful sleep throughout the night. When the nervous system relaxes, it can help your body and brain more readily enter the deepest and most restorative levels of quality sleep throughout the night.

6. Corrects Circadian Rhythm

One benefit associated with CBD is its ability to help people regulate their sleep wake cycle, also known as their circadian rhythm. Normally, a healthy circadian rhythm signals our bodies to be sleepy at night and alert during the day. If travel, stress, or other environmental factors cause the circadian rhythm to get interrupted or knocked off course, a CBD product often can help re-establish a healthy sleep wake cycle. In addition, because melatonin is the body’s key signal to the brain that it’s time to sleep or wake up, effective use of melatonin can help tremendously when it comes to regulating your circadian rhythm.

In the simplest of terms, a higher level of melatonin in the body signals that it’s time to sleep, while decreasing melatonin levels are a key signal to the body that it’s time to wake up. While melatonin engages with the melatonin 1a and 1b receptors, CBD interacts with CB-1 and CB-2 receptors, which help regulate both the immune system and the central nervous system. It’s through interaction with these receptors that CBD for sleep may also be able to influence and potentially help regulate the sleep wake cycle.

What is the Best Way to Mix CBD and Melatonin?

The best way to combine CBD and melatonin is to use an existing melatonin and CBD product from a manufacturer you know and trust. You should not try to combine a separate CBD product and melatonin supplement yourself at home. It’s important that each ingredient be blended in a proper ratio that allows it to complement the effects of the other. This is typically accomplished using high precision equipment, like those found in a laboratory.

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For example, you might try Farmer and Chemist’s All Is Gel Melatonin Soft Gels . These CBD softgels combine 25 milligrams of CBD with one milligram of melatonin and offer a convenient, natural way to get quality sleep. Plus, you don’t have to worry about measuring dosages. The combination of CBD and melatonin can help both your mind and body relax and begin to move toward restfulness. In addition, these CBD softgels can help with pain relief and hold anti-inflammatory properties.

As always, when adding a supplement to your daily regimen, a good recommendation is to begin with the lowest possible dose and build gradually until you reach your desired level of therapeutic effect. When it comes to sleep aids, you want to find the dose that helps you fall asleep quickly, stay asleep longer, and experience the most restful sleep stages, while also making sure you avoid excessive daytime sleepiness or difficulty waking.

CBD and Melatonin Can Be the Key to a Restful Night of Sleep

Sleep problems are nothing to take lightly. They can lead to long-term, serious health conditions and should be addressed immediately. Using a product at night that combines CBD and melatonin can be an effective way to guarantee you’re getting high quality, restful sleep.

As always, it’s important to talk with a health professional when adding a CBD product to your wellness regimen. This is especially true if you’d like to combine CBD with melatonin, and even more crucial if you also take other medications on a regular basis. The pharmacists at Farmer & Chemist can be a tremendous resource. Our knowledgeable team can talk you through potential risks and benefits associated with CBD’s addition to your existing lifestyle, plus how CBD and melatonin combo products may help you improve your sleep quality.

Don’t put restful sleep off another night—check us out today and start experiencing the sleep benefits CBD products can provide!

Melatonin and CBD Oil: Can It Help You Sleep Better?

When looking for better sleep, people will try just about anything. For years, science has supported the use of melatonin in cases of insomnia and other sleep disorders. But recently, CBD oil has been gaining traction as a potential solution to a range of problems, including sleep disturbances.

When combined, do CBD oil and melatonin help you sleep better? Are there side effects of using CBD oil and melatonin together? Moreover, how can you use CBD oil and melatonin safely?

In order to get the most from any supplement routine, it is important to understand the answers to these questions. Here’s what you need to know about CBD oil, melatonin, and getting a good night’s sleep!

CBD Oil and Melatonin Interaction

Melatonin and CBD oil both promote sleep, but work in different ways to do so. Unlike regular vitamins and supplements, when you take melatonin it is treated by the body as if it were created internally. Instead of breaking it down and converting it into something usable, your body is able to metabolize melatonin immediately, without further processing. The same is true for CBD oil.

CBD replicates your body’s own endocannabinoids in order to exert its therapeutic effects. Melatonin supplements work in a similar way, replicating endogenous melatonin to regulate your circadian rhythm, or natural sleep-wake cycle.

During normal waking hours, there is very little melatonin circulating in your body. Instead, there are other hormones like cortisol at work, which keep you alert and awake. As day turns to night and natural sunlight levels drop, the levels of melatonin in your system start to rise as the sun goes down, peaking overnight and slowly reducing toward the morning. Taking a melatonin supplement before bed increases the amount of melatonin in the body and can encourage rest and deeper sleep.

CBD oil promotes sleep by reducing cortisol levels and anxiety . Cortisol levels should naturally fall overnight, but if you’re overly stressed, they can spike and remain high, making falling asleep near impossible. CBD oil has been shown to inhibit the release of cortisol , and could help reduce the stress that’s barring you from a good night’s sleep. Since CBD oil can also help with anxiety, your overall stress levels should dip and remain lower, making relaxation and a good night’s sleep more achievable.

With all this in mind, taking CBD oil and melatonin together may create a powerful aid to fight insomnia. Because cannabidiol and melatonin act on different systems in the body, currently, the two substances can act synergistically to enhance the quality of your sleep. Melatonin signals your body that it is time to sleep, while CBD oil works in tandem to provide overall relaxation and calm. Together, they deliver a one-two punch to insomnia and sleep disturbances.

Side Effects of Using CBD oil and Melatonin

Neither CBD oil or melatonin have many recognised side effects. CBD oil is widely considered to be safe with little to no side effects . The World Health Organization published its own report on the use of CBD oil and found, “ … CBD does not produce the effects that are typically seen with cannabinoids such as THC… it is generally well tolerated, with a good safety profile.” Melatonin has few reported side effects , but some users may experience headaches, depression, or irritability. Combining CBD oil and melatonin may mitigate some of these side effects.

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Long-term use of melatonin is discouraged, as its efficacy decreases with chronic use. Courses of melatonin should be limited to three months or less. CBD can be used more chronically. If you decide to use the two supplements together, you may find that using both melatonin and CBD initially helps to establish good sleep patterns. Once these sleep patterns have been established, you could decrease your regimen to include CBD only.

Limited use of melatonin can help regulate your sleep-wake cycle, similar to hitting the refresh button on your natural circadian rhythm, times when your sleep cycle may be disrupted e.g. after international travel across time zones Regular use of CBD oil can regulate the body’s cortisol production, so you’ll feel less stressed day and night, which is great for your sleep hygiene and overall well being.

Melatonin and CBD are both metabolised via the cytochrome p-450 pathway, so any side effects of melatonin may theoretically be exacerbated by adding CBD. Perhaps you should include a warning about this and just a recommendation to start with a low dose of CBD if you are adding it to an existing melatonin supplement.

How to Safely Use CBD Oil and Melatonin Together

When combining CBD oil and melatonin it’s important to take dosage into account. As melatonin is often purchased in standardized doses it is easiest to maintain this amount and add CBD oil into your routine gradually. Start with a low dose of CBD oil and slowly increase your dosage over time if necessary—you don’t want to overload the body with too many sleep-inducing compounds at once. Allow your body and mind time to adjust to the effects of CBD oil.

Take note of whether taking CBD oil throughout the day or just at night is more beneficial for promoting sleep. You might consider keeping a sleep journal for the first month of using CBD oil and melatonin together to gauge which dosage and at what time(s) of day are most effective when it comes to using CBD for sleep.

Alternatively, you can purchase CBD products that already have melatonin included. This removes the need to delicately balance your quantities. If using these products, start with the dosage suggested in the information pamphlet and gradually increase until you experience the desired effect.

Melatonin is best used when you can get a full 8 hours of sleep. To avoid feeling groggy in the mornings, take your melatonin or CBD oil/melatonin combination product when you have enough time to devote to sleep. As with anything that can promote or induce sleep, be careful driving, operating heavy equipment or doing anything that requires extreme concentration until you know how the combination will impact you.

As a precaution, speak to your doctor before combining the two supplements. You can also speak with a cannabis doctor who can give you personalized recommendations on dosages and specific CBD products to help with sleep.

Best CBD Oil to Use with Melatonin

If you’re ready to try a product that contains CBD oil and melatonin, or want to purchase CBD oil to add into your existing melatonin routine, there are two main factors to consider: delivery method and quality.

For a melatonin-CBD hybrid product, the most common delivery formats are combination gummies , capsules, tinctures , and drops . Simply take the recommended dose prior to going to bed. Because capsules or gummies travel via the digestive system, they take longer to take effect. For this reason, take your melatonin-CBD combo gummies or capsule about an hour before bed to ensure you’ll feel the effects right on time.

If you don’t know when you’ll be going to bed, or want a little more flexibility, sublingual CBD-melatonin drops or tinctures may be best for you. These CBD products are absorbed directly into the bloodstream through the skin under the tongue and go to work in as little as a half hour. The only difference may be that you don’t feel the effects as strong or for as long as you would a gummy or capsule.

If you are already taking melatonin and want to add CBD oil, try starting with drops or a tincture. This format will allow you complete control over your CBD dose, ensuring you can gradually increase or decrease the amount as needed.

Before taking melatonin, CBD oil, or a combination of the two, consult with your physician. By having this conversation, you can determine if these are safe options for you and work out a potential starting dose. Both CBD oil and melatonin can interact with some commonly prescribed medications .

If you don’t see effects immediately, don’t lose sleep over it! Be patient and take your time adding CBD oil to your daily or nightly routine.

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