Increased risk of respiratory depression when combined with other drugs.
Some other drugs typically used in anxiety disorders—such as SSRIs and SNRIs for example—can be stimulating to the central nervous system, and people with a history of benzodiazepine dependency and withdrawal may be more sensitive to their adverse effects. They may cause further hyperexcitability in the already sensitized nervous system of a person in benzodiazepine withdrawal. Antidepressant sensitivity is more common in younger people and females, and the increase in anxiety caused by an antidepressant can result in a higher risk of suicide. For these reasons, initiating antidepressant therapy in someone suffering benzodiazepine withdrawal, and those who are benzodiazepine-sensitized or with a sensitive constitution in general should be approached with caution, if attempted at all.
Other medications, such as some antidepressants used for long-term management of anxiety and depression have been increasingly documented in clinical studies to have decreased effectiveness and a higher risk of adverse effects in people with a history of benzodiazepine dependency. In addition, anecdotal reports of this phenomenon are increasing with many psychoactive medications in patients with a benzodiazepine dependency or withdrawal syndrome history. In the benzodiazepine withdrawal support communities, there have been numerous anecdotal reports of reactions to other drugs, supplements, and the like which are commonly called “setbacks” or “reactions” and can be quite severe and sometimes long-persisting, causing what is described as a reactivation of distressing withdrawal symptoms.
This and other stimulating additives in over-the-counter cough and congestion remedies may cause increased anxiety.
Tools such as pharmacogenomic testing may be of some use in determining which medications may or may not be tolerated, however many benzodiazepine-injured patients report having reactions and sensitivities to medications they had no issues with prior to their benzodiazepine iatrogenic illness.
These have been known to cause severe and potentially permanent adverse effects, such as movement disorders known as Tardive Dyskinesia and the development of psychosis even in people without a history of psychotic disorders.
The addition of beta-blockers, antidepressants and antipsychotics should be avoided where possible.
It should also be noted that antidepressants and some other psychoactive drugs such as antipsychotics can also cause prescribed physical dependence and thus have a serious withdrawal syndrome upon discontinuation, and may also require a taper. Studies as recently as 2012 have determined that symptoms upon cessation of SSRIs and benzodiazepines are very similar, indicating that cessation of both of these types of drugs can provoke a potentially severe withdrawal syndrome. Some people can even develop psychotic symptoms after stopping an antipsychotic medication even if they’ve never had psychotic symptoms before.
This is adrenaline and is often contained in local anesthetics. Some local anesthetics do not contain epinephrine; ask your doctor.
WORLD BENZODIAZEPINE AWARENESS DAY | JULY 11 Educating communities on dangers of prescribed benzodiazepines OTHER MEDS & “ALTERNATIVES” TO BENZODIAZEPINES Unfortunately, there is no known
Ironically, withdrawal symptoms that occur when quitting Xanax include anxiety and panic attacks — the very reasons it’s prescribed in the first place!
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You can see the list at Drugs.com.
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